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Each year pharmaceutical companies invest billions of dollars in clinical trials of drugs used for the treatment of central nervous system diseases. Due to enormous progress in basic pharmaceutical research in recent years, controlled tests of new medications are flourishing and these trials have rapidly become an intense focus of practical medical research.
Aware of the complexities presented in the design, execution, and evaluation of clinical trials, Marc Hertzman and Douglas E. Feltner bring together a collection of essays that dissect the scientific, psychosocial, political, and ethical concerns that must be examined for any CNS trial. The internationally known contributors examine concerns about ethics and cost; the FDA and its regulatory impact; and the implementation of a variety of trials, for disorders such as schizophrenia, alcoholism, eating disorders, insomnia, and aggression.
The editors carefully consider important social issues including the considerations related to women's special needs; and the relative merits of psychotherapy and medications. The Handbook of Psychopharmocology Trials provides an up-to- date and stimulating exploration of important issues on the subject of CNS Clinical trials.
Review: Working the Diaspora is a welcome contribution to the study of labor and culture under slavery. Spanning the colonial through the antebellum period, Knight argues that Africans brought much more than brute strength to their work in sugar, rice, tobacco and indigo fields. By carefully contextualizing his study of labor practices in the Americas in the African past, Knight offers a compelling argument for the crucial role of African knowledge in the building of staple crop agriculture in the Americas.
In a study that is archivally deep and analytically rich, Knight significantly expands our understanding of the role of African expertise in the creation of the black Atlantic. -Jennifer L. Morgan, author of Laboring Women: Gender and Reproduction in New World Slavery
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